Assoc. Prof. Ondřej Sedláček’s group focuses on the development of highly functional polymeric materials that respond to external stimuli such as light, temperature, or pH. These “smart” polymers have applications in biomedicine, for instance in the design of targeted drug delivery systems.
The team employs an interdisciplinary approach, combining polymer and organic chemistry, biochemistry, and medicine. They use advanced synthetic methods, such as photocatalyzed controlled radical polymerization and cationic ring-opening polymerization, to produce polymers with precisely defined architectures – linear, branched, or self-assembling block copolymers.

Assoc. Prof. Ondřej Sedláček
Dr. Sedláček leads projects funded by GAČR and AZV, with a focus on developing innovative materials that can enable new therapeutic strategies and targeted biomedical applications.
Learn more: Polymer and Biomaterials Synthesis Group
Biocentre is financially supported by the National Restoration Plan; Investment identification number: Z332802000005.